Prof. Hakan Sözen, Md



Prof. Hakan Sözen, Md



Foreign Languages Known (Score and Year): English (78.5, 2010 ÜDS)

Certifications Obtained:

  • Robotic surgery certificate
  • Kidney transplant certificate
  • Liver transplant certificate

Profession:

General Surgery, Transplantation

Degree Department/ProgramUniversity
LicenceCERRAHPASA FACULTY OF MEDICINEIstanbul University
Master DegreeDepartment of GENERAL SURGERY, CERRAHPASA FACULTY OF MEDICINEIstanbul University
Expertise in MedicineDepartment of, GENERAL SURGERY, CERRAHPASA FACULTY OF MEDICINEIstanbul University
Assoc.Prof degreeGeneral SurgeryGazi University
Prof. degreeGeneral SurgeryGazi University

Tasks:

Job Title                              Position
Res.Assist. Cerrahpasa Faculty of Medicine, Istanbul University
Dr.Assist.Department of General Surgery, Cerrahpasa Faculty of Medicine, Istanbul University
Clinical ObserverTransplantation, Department of Surgery, University of Minnesota, USA

University of Minnesota Department of Surgery, Transplantation Clinic

Clinical and surgical study on kidney, liver, pancreas transplantations.

Research FellowDiabetes Institute for Immunology and Transplantation, University of Minnesota, USA

University of Minnesota Department of Surgery, Diabetes Institute

Tolerance development in mouse and monkey models,

Experimental research on chimerism, bone marrow transplantation, islet cell transplantations, skin transplantation.

Clinical FellowDepartment of Transplantation, Department of General Surgery, Baskent University
Instructor Member ofTransplantation Center, Gazi University
Kidney transplant managerTransplantation Center, Gazi University
Assoc. Prof degreeGeneral Surgery, Transplantation Center, Gazi University
Liver transplant managerTransplantation Center, Gazi University
Prof. DegreeGeneral Surgery, Gazi University
AssignmentIstanbul Florence Nightingale Hospital Liver Transplantation

Performed in Projects:

  1. Plasma homocysteine levels in living kidney donors before and after uninephrectomy (clinical research). National Institutes of Health Program Project Grant in Transplantation (NIH DK 13083-31), “Organ Transplantation in Animals and Man.” Project Designer .
  2. Protective effect of resveratrol, a red wine constituent polyphenol, on rats subjected to portal vein thrombosis (experimental study). Project Designer .
  3. Effect of nipruss ® as nitric oxide donor on colonic anastomosis healing in a diabetic rat model (experimental study). Master thesis.Project Designer .
  4. Resistance to the induction of mixed chimerism in spontaneously diabetic NOD mice depends on the CD40/CD154 pathway and donor MHC disparity (experimental study). NIH (R21AI055469) with JDRF Center for Islet Transplantation at the University of California, San Francisco, the University of Minnesota. Project Implementer .
  5. A substantial level of donor hematopoietic chimerism is required to protect donor-specific islet grafts in diabetic NOD mice (experimental study). Project Implementer.
  6. Inducing tolerance to MHC-matched allogeneic islet grafts in Diabetic NOD mice by simultaneous islet and bone marrow transplantation under nonirradiative and nonmyeloablative conditioning therapy. (experimental study). Project Implementer.
  7. Rapamycin and T cell costimulatory blockade as post-transplant treatment promote fully MHC-mismatched allogeneic bone marrow engraftment under irradiation-free conditioning therapy. (experimental study). Project Implementer. Supported by Juvenile Diabetes Foundation International and the American Diabetes Association.
  8. Blockade of the CD40/CD154 pathway enhances T-cell-depleted allogeneic bone marrow engraftment under nonmyeloablative and irradiation-free conditioning therapy (experimental study 2009 – 2012). Project Implementer.
  9. Multicenter study (clinical investigation) evaluating the safety and tolerability of the use of valganciclovir in the prevention of cytomegalovirus disease in solid organ transplant patients. Prot number: ML 21922.
  10. Multicenter follow-up study investigating the efficacy and safety of PSI group drugs in kidney transplant patients (clinical study 2008-2012). CRAD001ATR02. Responsible Researcher.
  11. Kidney Collaboravite Transplant Study. Germany. (clinical research. Responsible Researcher. 2016-)
  12. Insufficiency of organ donation in Turkey and its causes . Clinical Research Project. (project assistant responsible/supervisor).2016
  13. Development of statistical decision support systems for donor and donor matching in cadaveric kidney transplantation. 2018. TUBITAK 1003. Clinical Research Project. (project assistant responsible/supervisor)

Administrative Duties:

Kidney transplant managerTransplantation Center, Gazi University
Liver transplant managerTransplantation Center, Gazi University

Memberships to Scientific Organizations:

  1. EUROPIAN SOCIETY OF TRANSPLANTATION (ESOT)
  2. AMERICAN SOCIETY OF TRANSPLANTATION (AST)
  3. TURKISH ORGAN TRANSPLANT ASSOCIATION (TOND)
  4. NATIONAL SURGICAL ASSOCIATION
  5. TIGED



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