Cirrhosis is irreversible scarring of the liver, posing a potential life threatening risk. Approximately 80% to 90% of the liver can be damaged and replace with scarred (death) tissue in an advanced stage. Cirrhosis is caused by alcohol, viral infection, (Hepatitis B, C), toxic substances (e.g. medications, excess copper or iron in the liver), or liver damage of years from blockage of biliary system. The liver goes through a progressive scarring, replacing all normal liver cells gradually.
In most of the cases, the above causes are usually resulted in treatable Hepatitis. However, in case of failure to eliminate or treat the trouble factor, cirrhosis occurs and it is usually too late to alter the course of the disease.
It initially presents with symptoms including fatigue, drowsiness, yellowing of eyes and urine (mild jaundice), swollen feet, itching, and anemia (lower hemoglobin). In later stages, the patient may suffer from many life-threatening complications such as hematemesis, swollen stomach leading to serious infection due to ascites, mental disorder, coma, severe jaundice, and renal dysfunction.
The patient may also present with hemorrhage due to lower levels of prothrombin, a liver protein, and low blood platelet count. Both are critical to normal blood-clotting.
Although cirrhosis means irreversible damage of the liver, an individual in an early stage of cirrhosis (stage Child A or early Child B) is likely to have an active life for long years through an appropriate treatment planned by liver specialists. On the other hand, the progressed cirrhosis or cirrhosis in stage Child C indicates liver transplant requiring an expert opinion
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Group Florence Nightingale Hospitals Ltd UK 2020, all rights reserved.
Group Florence Nightingale Hospitals Ltd UK 2020, all rights reserved.